Skip to main content
2025 ASCRS Annual Scientific Meeting Main banner
Final Program


Visit ASCRS U
Icon Legend
This session is not in your schedule.
This session is in your schedule. Click again to remove it.
Presentation Icons
CME
CME
Invitation/Ticketed Event
Invitation/Ticketed Event
Invited Lectureship
Invited Lectureship
Award Recipient
Award Recipient
Self-Assessment
Self-Assessment
Social
Social
Industry
Industry
Back

Session: ePoster: Benign Anorectal 4 (Sun225)

EP493 - Curing Cryptoglandular Anal Fistulas—Is It Possible Without Surgery?

Sunday, May 11, 2025
2:41 PM – 2:46 PM PT
Location: Monitor 4, Sails Pavilion, Upper Level

    ePoster Presenter(s)

  • CHUANG WU, 22GDDAEA1403 (he/him/his)

    Deputy Director of Surgery
    Shanghai Baoshan District Hospital of Integrated Traditional Chinese and Western Medicine
    Shanghai, Shanghai, China (People's Republic)

    All of the relevant financial relationships listed below have been mitigated.
    This individual has no financial relationships with ineligible companies.

    • Author(s)

  • ZM

    Zubing Mei, n/a

    Associate Chief Physician of Surgery
    Shuguang Hospital, Shanghai University of Traditional Chinese Medicine
    Shanghai, Shanghai, China (People's Republic)

    Disclosure information not submitted.

    • Senior Author(s)

  • Zhenyi Wang, MD,PHD (he/him/his)

    Director of Anorectal Medicine Department
    Department of Anorectal Surgery, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
    Shanghai, Shanghai, China (People's Republic)

    All of the relevant financial relationships listed below have been mitigated.
    This individual has no financial relationships with ineligible companies.

All of the relevant financial relationships listed below have been mitigated.
CHUANG WU, 22GDDAEA1403: This individual has no financial relationships with ineligible companies.
Zhenyi Wang, n/a: This individual has no financial relationships with ineligible companies.
Image or Table (Do Not add text here):

Purpose/Background: Empirical reviews suggested that cryptoglandular anal fistulas require surgical resolution. However, some reports have indicated the possibility of nonsurgical and conservative treatment, which is discussed in this review.

Methods/Interventions: This review explores the potential of nonsurgical approaches for curing anal fistulas through bacterial inhibition and immunomodulation. The longstanding cryptoglandular theory has been a subject of controversy, prompting the reevaluation of conventional surgical interventions for anal fistulas. The review was conducted through database searches, including Medline, EMBASE, PubMed, and the Cochrane Library.

Results/Outcomes: Emerging evidence suggests that targeting the anaerobic environments present in anal fistulas and perianal abscesses and eradicating bacteria and their by-products may be critical for successful treatment. Immunomodulatory strategies show promise as a potential avenue for the nonsurgical management of anal fistulas.

Conclusion/Discussion: Ongoing developments in pharmacological research offer opportunities for alternative treatment options, shedding light on the prospects of noninvasive anal fistula management.